Larazotide Acetate Capsules (Ultimate GI Repair)

"Elite Gut Healing Stack"

This product features a synergistic combination of the most powerful gastrointestinal tract healing ingredients on the market, featuring clinical doses of the powerful peptides BPC-157 and Larazotide Acetate!

benefits

How

Larazotide Acetate Capsules (Ultimate GI Repair)

can help you:

Fights gluten exposure, heals leaky gut and reduces Gi wide inflammation. Larazotide acetate is a novel, locally acting non-systemic, synthetic 8-amino acid oral peptide, discovered during functional screening of synthetic Vibrio cholera related peptides. Larazotide acetate is a first-in-class tight junction (TJ) regulator under development as an adjunct to a GFD. Larazotide acetate appears to prevent opening of intestinal TJs by promoting TJ assembly and actin filament rearrangement, which prevents gluten from reaching the intestinal submucosa and triggering an inflammatory response.

Gut Health

  • BPC-157 (body protection compound) is a small molecule peptide that is found naturally in gastric juices/stomach acid. This peptide protects, heals and restores tissues by the building of new blood vessels and upregulating growth factors such as Vascular Endothelial Growth Factor (VEGF), Epithelial Growth Factor (EGF), Nerve growth factor (NGF) (1).
  • Larazotide acetate is an oral peptide derived from zonula occludens that acts as a tight junction regulator and zonulin antagonist.
    It binds to receptors of apical intestinal cells and antagonises zonulin, preventing the opening of the epithelial intestinal tight junctions caused by gluten/gliadin, glyphosate, pro-inflammatory cytokines, zonulin bacterial antigens such as lipopolysaccharide (LPS) and bacterial dysbiosis (2).
  • Larazotide acetate is being touted as a promising non-dietary treatment for coeliac disease and has passed multiple clinical trials (3).
  • Quercetin has also been shown to enhance gut barrier function by having a “sealing” effect due to its role in the assembly and expression of tight junction proteins: zonula occludens-1, occludin, junctional adhesion molecule-A, claudin-3 (4).
  • Tributyrin/Butyrate keeps your colon cells healthy, reduces inflammation, boosts your immune system, and improves gut health by stimulating mucosal repair and providing more energy to the cells of the GI tract (5).
  • Tributyrtin enhances the colonic defense barriers by:
    - Increasing mucus production
    - Decreasing epithelial hyper-permeability by promoting tight junctions and tight junction repair
    - Increasing villus height and villus height: crypt depth (Wang et al. 2019)
    - Decreasing pH (6).

Longevity

  • Tributyrin is anti-Inflammatory (7):
    - Histone deacetylase (HDAC) inhibitor.
    - Inhibits the NFkB inflammasome, thereby protecting the DNA from reactive oxygen species.
    - Cyclooxygenase 2 (COX-2) inhibition; reduces pro-inflammatory series 2 and 4 eicosanoids.  
    - Activates glutathione s-transferases (GST), an enzyme that aids in detoxification. GST speeds up the linking of toxic compounds with glutathione (GSH), thus forming a less reactive substance.
    - Activates p53 transcription factor and activates p21 (cell cycle arrest); via these mechanisms and HDAC inhibition, studies have shown butyrate to prevent the progression of colon cancer in animal studies.
    - Improves mitochondrial function.
  • Quercetin: By blocking mast cell degranulation, quercetin can also allow the Di-Amine Oxidase (DAO) enzyme to catch up to the backlog of excess histamine, and help reduce food sensitivities/reactions and reduce the burden on the immune system (8).
  • Zn-C is a synthesized chelate of the mineral zinc and the amino acid L-carnosine (a dipeptide of beta-alanine and l-histidine) in a 1:1 ratio. For over 20 years, zinc carnosine has been used in Japan for promoting healing of gastric mucosa (9).
DOSAGE STRATEGY

How to use

Larazotide Acetate Capsules (Ultimate GI Repair)

2 capsules per serve. 1 with breakfast and 1 after dinner.

General population:

2 capsules per serve. 1 with breakfast and 1 after dinner.

Adults:

2 capsules per serve. 1 with breakfast and 1 after dinner.

-BPC-157 Pentadecapeptide – 700mcg -AT1001 Larazotide Acetate – 500mcg -PEPZIN: Zinc L-Carnosine 200mg (as 156mg L-Carnosine and 43mg zinc) -Quercetin Anhydrous – 400mg -Tributyrin – 398.8mg
mg of

Ideal for:

1 week for maximum benefits.

Coeliac, Bloating, Gas, Diarrhoea, Constipation.

CAUTIONS

Larazotide Acetate Capsules (Ultimate GI Repair)

safety and
medication interactions.

Buy from an Ergogenic trusted vendor

Fights gluten exposure, heals leaky gut and reduces Gi wide inflammation. Larazotide acetate is a novel, locally acting non-systemic, synthetic 8-amino acid oral peptide, discovered during functional screening of synthetic Vibrio cholera related peptides. Larazotide acetate is a first-in-class tight junction (TJ) regulator under development as an adjunct to a GFD. Larazotide acetate appears to prevent opening of intestinal TJs by promoting TJ assembly and actin filament rearrangement, which prevents gluten from reaching the intestinal submucosa and triggering an inflammatory response.

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Ultimate GI Repair is something that I recommend for someone who is battling gluten sensitivity or general gut related problems such as bloating, gas, wind and/or IBS. It's amazing to see Larazotide acetate in Australia,

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