X

Looking for something?

Search our website to find what you need!

Other resources: Supplement Products, Webinars, Podcast and Blog.

Benefits

How To Use

Evidence

Purchase now

Purchase now

L-Tetrahydropalmatine

"The Mind Silencer"

Levo-Tetrahydropalmatine (L­-THP) is the active compound found in the Corydalis Yanhusuo herb, endemic to China. There are numerous L-THP benefits that people are talking about today. In China, L-THP is marketed and sold as an anti-stress and pain-relieving compound and is sometimes called Yan Hu Suo.

Benefits

How To Use

Evidence

benefits

How

L-Tetrahydropalmatine

can help you:

L-THP is used primarily for its ability to help reduce feelings of stress, to improve mood status, and sometimes for its ability to reduce sensations of pain. In China, L-THP is used for reducing symptoms of pain and as a muscle-relaxant and is sold under the name Rotundine. L-THP is also a powerful anti-inflammatory compound, meaning that it may help to promote good health.

Brain

  • L-tetrahydropalmatine reduces nicotine self-administration and reinstatement in rats, thereby indicating powerful anti-addiction properties (1).
  • Four weeks of l-THP treatment significantly ameliorated the severity of PAWS—specifically, somatic syndrome, mood states, insomnia, and drug craving, in comparison to a placebo group, in terms of drug addiction (2).
  • L-Tetrahydropalmatine reduces the development of anxiety and depression-related symptoms induced by single prolonged stress (3).
  • L-THP exerts anxiolytic effects via potential interaction with the benzodiazepine binding site on the gamma-aminobutyric acid (GABAA) receptor (4).

Anti-inflammatory

  • L-THP exerts a prominent anti-inflammatory agent induced by lipopolysaccharide (5).
  • L-THP has been used for the treatment of headache and other mild pain. However, little is known about its analgesic effect on chronic pain and its mechanism. It was reported that L-THP exerts remarkable antihyperalgesic effects on neuropathic and inflammatory pain in animal models (6).

Longevity

  • L-THP has been reported to attenuate PTSD-induced changes in gene expression, such as those involving DA, serotonin, and acetylcholine, in the amygdala and hippocampus (7).
  • L-THP works as a powerful cardio-protective supplement, helping to prevent damage to the heart under a variety of stresses (8).
DOSAGE STRATEGY

How to use

L-Tetrahydropalmatine

Take one capule, 30-60 minutes before sleep

General population:

Take one capule, 30-60 minutes before sleep

Adults:

Take one capule, 30-60 minutes before sleep

Need to find the right dose for you?

Consider getting a custom stack designed.

50mg
mg of

Ideal for:

This produt deliers very rapid effects. Best cycled.

Stressed individuals, Sleep, Overexcitation.

CAUTIONS

L-Tetrahydropalmatine

safety and
medication interactions.

Safety assessment

Pharmacokinetics and Safety Assessment of L-Tetrahydropalmatine in Drug Users: A Randomized, Double-blind, Placebo Controlled Study

Safety studies

.
Pharmacokinetics and Safety Assessment of L-Tetrahydropalmatine in Cocaine Users: A Randomized, Double-blind, Placebo Controlled Study

Medication interactions

  • Please consult with your healthcare professional. This can have dangerous interactions with medications.

Side Effects / Contraindications

  • Please consult with your healthcare professional. This can have dangerous interactions with medications.

Allergies

  • None Known.

Buy from an Ergogenic trusted vendor

L-THP is used primarily for its ability to help reduce feelings of stress, to improve mood status, and sometimes for its ability to reduce sensations of pain. In China, L-THP is used for reducing symptoms of pain and as a muscle-relaxant and is sold under the name Rotundine. L-THP is also a powerful anti-inflammatory compound, meaning that it may help to promote good health.

Purchase nowPurchase nowPurchase nowPurchase nowPurchase nowBUY NOWPurchase now

This formuia encompasses a wide range of anxiolytics and sedatives that induce a very profound deep sleep. No tolerance noticed.

Need something tailored to your needs?

Get a Custom Stack, designed just for you, from a library of over 2,000 ingredients, from trusted vendors.

LEarn more

Scientific Citations

1
l-tetrahydropalmatine reduces nicotine self-administration and reinstatement in rats.
2
Medication of l-tetrahydropalmatine Significantly Ameliorates Opiate Craving and Increases the Abstinence Rate in Heroin Users: A Pilot Study
3
L-Tetrahydropalmatine Ameliorates Development of Anxiety and Depression-Related Symptoms Induced by Single Prolonged Stress in Rats
4
Evaluation of the anxiolytic properties of tetrahydropalmatine, a Corydalis yanhusuo compound, in the male Sprague-Dawley rat.
5
Tetrahydropalmatine inhibits pro-inflammatory mediators in lipopolysaccharide-stimulated THP-1 cells.
6
L-Tetrahydropalmatine alleviates mechanical hyperalgesia in models of chronic inflammatory and neuropathic pain in mice.
7
Effects of tetrahydropalmatine on post-traumatic stress disorder-induced changes in rat brain gene expression.
8
l-Tetrahydropalmatine, an Active Component of Corydalis yanhusuo W.T. Wang, Protects against Myocardial Ischaemia-Reperfusion Injury in Rats