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Evidence

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Spermidine Capsules (Anti-Aging Supplement)

"The Supplement That Delays Ageing"

Spermidine is a polyamine that carries a positive charge that interacts with negatively charged molecules such as RNA, DNA, and proteins. It synchronizes a myriad of biological processes, thus maintaining membrane integrity and controlling volume and intracellular pH. Polyamines play significant roles in cell metabolism, cell growth, proliferation, and survival. The polyamine levels in organisms vary per organism and decline throughout aging.

Benefits

How To Use

Evidence

benefits

How

Spermidine Capsules (Anti-Aging Supplement)

can help you:

Spermidine inhibits 5 of the 9 hallmarks of aging and also triggers autophagy - the process by which your body gets rid of damaged cells and proteins.⁣ ⁣ It has been studied for its role in improving cognitive function, immune function in the elderly, mitochondrial function, DNA protection and much more.⁣ After 2-3 months of constant use people have reported that their hair and eyelashes are thicker, nails are stronger and cellulite seems to be disappearing.⁣

Longevity

  • Spermidine is a potent polyamine-rich compound known for for boosting autophagy which is the body's cellular renewal and recycling process that slows as we age. It’s found in high quantities in the diets of some of the longest-lived people in the world (1).
  • Spermidine supplementation shows significant reduction of weight gain, visceral fat, glucose intolerance, and insulin insensitivity in mice fed a Western style high-fat diet, when compared with controls. Such evidence suggests that, in mice at least, spermidine could protect against obesity and type 2 diabetes, which echoes the benefits of other autophagy-promoters (2).
  • Studies in mice show that, in addition to improving lifespan by 25%, spermidine supplementation decreases the risk of liver fibrosis and cancer, even in subjects exposed to tumor-promoting chemicals. Human observational studies also link intake of spermidine-rich foods with reduced risk of colon cancer.

Brain Health

  • In flies and worms spermidine feeding protects against neurodegeneration related to Parkinson’s disease. Accumulation of alpha-synuclein protein has often been implicated as a potential toxic driver of this disease, but spermidine can reduce the associated loss of motor function and early mortality in flies. It also prevents alpha-synuclein-induced loss of dopaminergic neurons in worms (3).
    ‍
  • Results of another study showed a significant correlation between the spermidine concentration and the mini-mental state examination score (p = 0.025). On the basis of the dependence demonstrated it can be concluded that spermidine might be suitable as a biomarker for the diagnosis of neurocognitive changes (senile dementia or Alzheimer's disease (4).
DOSAGE STRATEGY

How to use

Spermidine Capsules (Anti-Aging Supplement)

1-10mg daily.

General population:

1-10mg daily.

Adults:

1-10mg daily.

Need to find the right dose for you?

Consider getting a custom stack designed.

1mg
mg of

Ideal for:

We recommend taking our spermidine supplement with liquid at mealtime. You can also open the capsules and mix the contents with a cold or room temperature drink or smoothie.

Anti-aging, health addicts.

CAUTIONS

Spermidine Capsules (Anti-Aging Supplement)

safety and
medication interactions.

Safety assessment

Extremely strong safety profile.

Safety studies

Not available.

Medication interactions

Our spermidine supplement contains concentrated wheat germ and is not suitable for individuals with Celiac disease or wheat allergy. It may not be suitable for individuals diagnosed with SIBO. Please consult your healthcare practitioner.



Side Effects / Contraindications

Our spermidine supplement contains concentrated wheat germ and is not suitable for individuals with Celiac disease or wheat allergy. It may not be suitable for individuals diagnosed with SIBO. Please consult your healthcare practitioner.


Allergies

Our spermidine supplement contains concentrated wheat germ and is not suitable for individuals with Celiac disease or wheat allergy. It may not be suitable for individuals diagnosed with SIBO. Please consult your healthcare practitioner.


Buy from an Ergogenic trusted vendor

Spermidine inhibits 5 of the 9 hallmarks of aging and also triggers autophagy - the process by which your body gets rid of damaged cells and proteins.⁣ ⁣ It has been studied for its role in improving cognitive function, immune function in the elderly, mitochondrial function, DNA protection and much more.⁣ After 2-3 months of constant use people have reported that their hair and eyelashes are thicker, nails are stronger and cellulite seems to be disappearing.⁣

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I am in the process of reviewing the effects of Spermidine. I am blown away by the amount of research that is being released as we speak. Keep an eye out on my YouTube channel for my in-deoth review!

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Scientific Citations

1
Spermidine Promotes Cardioprotective Autophagy
2
Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens
3
Spermidine protects against α-synuclein neurotoxicity
4
Spermidine in dementia : Relation to age and memory performance