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Benefits

How To Use

Evidence

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Calcium D-Glucarate

“Detoxify Toxins Safely”

Calcium-d-Glucarate (CDG) is a natural substance produced by all mammals, including humans. It is in certain foods, such as oranges and cruciferous vegetables. As toxin exposure has increased, humans need more calcium-d-glucarate to help excrete extra toxins. Your liver works hard for you. Even if you don’t drink alcohol or work amongst harsh chemicals, the toxins you inadvertently breathe, ingest, drink, and even slather on your skin are a burden on your liver and this can start to take its wreck havoc on every single system in the body. Calcium D Glucarate is the number one nutrient to inhibit beta-glucuronidation, which is essential for optimal health.

Benefits

How To Use

Evidence

benefits

How

Calcium D-Glucarate

can help you:

Calcium D-Glucarate is essential for anyone commited to reducing exposure to harmful xenoestrogens, plastics and hormones. It can improve energy levels, libido and liver function.

  • Calcium D-glucarate, inhibits beta-glucuronidase. By inhibiting beta-glucuronidase, it ensures that excess hormones are excreted from the body and not reabsorbed (2).
  • Can purge excess xenoestrogens from the body, which are found in a variety of sunscreen, beauty products, shampoo and even soaps (3).

Hormonal Optimisation

  • High levels of beta-glucuronide increase the number of estrogen receptors. Calcium D-Glucarate is the best nutrient to inhibit this enzyme directly, leading to optimal estrogen balance (1).
  • Tamoxifen, which is often used by bodybuilders to reduce estrogen, can possibly be replaced with Calcium D-Glucarate, as research has proven the efficacy (4).
  • Oral administration of large doses of Calcium D-Glucarate have been shown to lower serum estrogen levels in rats by 23 percent (9).

Longevity

  • D-glucarates have been shown to significantly reduce total serum cholesterol in rats by as much as 12-15 percent and LDL-cholesterol by 30-35 percent. Preliminary results in humans show D-glucarate reduced total serum cholesterol up to 12 percent, LDL cholesterol up to 28 percent, and triglycerides up to 43 percent (10).
  • High beta-glucuronidase activity has been linked to low D-glucaric acid levels, which in turn is associated with an increased risk for various cancers (7).
  • Inhibition of beta-glucuronidase ultimately results in potentially decreasing the risk of carcinogenesis, such as breast, colon and prostate cancer (7, 8).
  • Researchers concluded that calcium D-glucarate may prevent lung cancer in tobacco smokers and ex-smokers by enhancing apoptosis and suppressing the acute inflammation and proliferation induced by tobacco-related carcinogens (5).
DOSAGE STRATEGY

How to use

Calcium D-Glucarate

100-2000mg daily.

General population:

500mg daily

Adults:

500mg daily

500mg
mg of

Ideal for:

Calcium-D-Glucarate shines when using for consecutive days, followed by a period of abstinence.

Athletes, Longevity, Poor Liver Function

CAUTIONS

Calcium D-Glucarate

safety and
medication interactions.

Safety assessment

Currently no known toxicity associated with high doses of Glucaric acid supplementation in research animals (30). Use during pregnancy should also be avoided.

Safety studies

Not available.

Medication interactions

Currently no known toxicity associated with high doses of Glucaric acid supplementation in research animals (30).
Use during pregnancy should also be avoided.

Side Effects / Contraindications

Currently no known toxicity associated with high doses of Glucaric acid supplementation in research animals (30).
Use during pregnancy should also be avoided.

Allergies

None known.

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Calcium D-Glucarate is essential for anyone commited to reducing exposure to harmful xenoestrogens, plastics and hormones. It can improve energy levels, libido and liver function.

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Calcium D-Glucarate is useful during periods of toxin exposure and can signficantly improve liver function (thus energy levels).

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Other Resources

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Scientific Citations

1
Calcium-D-glucarate.
2
Effect of calcium glucarate on beta-glucuronidase activity and glucarate content of certain vegetables and fruits.
3
Detoxifying cancer causing agents to prevent cancer.
4
Detoxifying Cancer Causing Agents to Prevent Cancer
5
The biological role of D-glucaric acid and its derivatives: Potential use in medicine
7
Calcium-D-glucarate.
8
Effects of 5-fluorouracil, leucovorin, and glucarate in rat colon-tumor explants.
9
Dietary glucarate as anti-promoter of 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis.
10
D-Glucaric acid content of various fruits and vegetables and cholesterol-lowering effects of dietary D-glucarate in the rat
30
A comparative study of antioxidative activity of calcium-D-glucarate, sodium-D-gluconate and D-glucono-1,4-lactone in a human blood platelet model.