Akkermansia Muciniphila Probiotic (Insulin Sensitivity)

Fat Melting Probiotic Strain

Recently, Akkermansia has been getting a lot of attention because several studies have linked it to leanness, as well as a resistance to obesity and type 2 diabetes.

benefits

How

Akkermansia Muciniphila Probiotic (Insulin Sensitivity)

can help you:

A. muciniphila is a recent discovery, but still a pretty cool bacterium with massive potential. It’s found throughout your gastrointestinal tract, particularly in the large intestine. It’s associated with lean individuals, and for that reason is believed to have roles in preventing the development of metabolic disease.

Gut Health

  • Akkermansia doesn’t deplete the mucus layer by eating it. Quite the opposite: they actually encourage the cells there to make even more, strengthening the layer further and giving us—their hosts—all the health benefits that come with having a tough gut barrier (1).
  • Produces short chain fatty acids (SCFAs), an energy source for other gut bacteria (2).
  • When Akkermansia breaks down mucins, it turns them into short-chain fatty acids (SCFAs), including acetate, which your gut lining cells love Acetate is used by other beneficial bacteria like Faecalibacterium prausnitzii, to make butyrate, which is an essential energy source for the cells lining your gut. This kind of process is called cross-feeding (3).

Insulin Sensitivity

  • its abundance suggests improved metabolic disorders, such as metabolic endotoxemia, adiposity insulin resistance and glucose tolerance. The role of A. muciniphila is implicated in declining aortic lesions and atherosclerosis (4)
  • The supplementation with A. muciniphila is sufficient to protect mice against high sucrose-induced impairment of glucose intolerance by decreasing βCDCA and increasing insulin secretion and FGF15/19. Furthermore, βCDCA inhibits insulin secretion and FGF15/19 expression (5).
  • After three months of supplementation, A. muciniphila reduced the levels of the relevant blood markers for liver dysfunction and inflammation while the overall gut microbiome structure was unaffected. In conclusion, this proof-of-concept study shows that the intervention was safe and well tolerated and that supplementation with A. muciniphila improves several metabolic parameters (6).
DOSAGE STRATEGY

How to use

Akkermansia Muciniphila Probiotic (Insulin Sensitivity)

Take one capsule daily with food for at least 12 weeks

General population:

Take one capsule daily with food for at least 12 weeks

Adults:

Take one capsule daily with food for at least 12 weeks

Need to find the right dose for you?

Consider getting a custom stack designed.

100 million AFU per capsule
mg of

Ideal for:

Take one capsule daily with food for at least 12 weeks

Fat loss, gut health, metaboiic health

CAUTIONS

Akkermansia Muciniphila Probiotic (Insulin Sensitivity)

safety and
medication interactions.

Safety assessment

Strong safety profile

Safety studies

Not available.

Medication interactions

  • None known, although please consult your healthcare professional before using this product.

Side Effects / Contraindications

  • None known, although please consult your healthcare professional before using this product.

Allergies

  • Allergy to chicory inulin.

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A. muciniphila is a recent discovery, but still a pretty cool bacterium with massive potential. It’s found throughout your gastrointestinal tract, particularly in the large intestine. It’s associated with lean individuals, and for that reason is believed to have roles in preventing the development of metabolic disease.

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Pendulum Akkermansia holds a patented strain of Akkermansia muciniphila; it serves as one of the unique strains discovered through high-resolution DNA sequencing, unavailable anywhere else.

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Scientific Citations