Search our website to find what you need!
Other resources: Supplement Products, Webinars, Podcast and Blog.
Adrafinil was discovered in 1974 in France. Adrafinil is a wakefulness-promoting drug that appears to have impressive nootropic properties. Used responsibly, it may be an effective tool for supporting lengthy mentally demanding tasks.
Adrafinil is a stimulant based eugeroic that can increase energy, prevent fatigue, and enhance wakefulness, without causing anxiety or other side effects that are typically associated with stimulants. It may also improve mood, focus, and learning ability, and may even help keep your brain healthy.
•The mechanism of adrafinil appears to rely on postsynaptic α-adrenergic activity, since an increase in locomotion caused by adrafinil is blocked by prazosin (α1 antagonist), yohimbine (α2 antagonist), or phenoxybenzamine (mixed α-antagonist) (1).
•Blocking the synthesis of catecholamines (with α-methyltyrosine) does not prevent the actions of adrafinil, providing further evidence differentiating the actions of adrafinil as distinct from that of amphetamine-like stimulants (2).
•Since adrafinil lacks anxiogenic (anxiety producing) effects and has greater efficacy during periods when research animals would typically be asleep, the effect of adrafinil on locomotion is thought to be secondary to promoting wakefulness (3).
•It stimulates histamine (HA), norepinephrine (NE), serotonin (5-HT), dopamine (DA), and orexin systems in the brain (4).
•Via acting as a potential dopamine reuptake inhibitor, it blocks the mechanism by which dopamine is absorbed by the body and rendered inert, thereby enhancing energy levels (5).
•Adrafinil operates much the same way as amphetamines when it comes to keeping you awake and alert, without the major side effects (6).
General population:
250mg - 400mg
Adults:
250mg - 400mg
Ideal for:
Best used infrequently. However, chronic use of adrafinil can be considered as not addictive with a low potential for abuse. Tolerance to many of the effects of adrafinil develops with prolonged and repeated use.
Students, entrepreneurs.
The long-term safety and effectiveness of modafinil (adrafinil's active component) as a drug of regular usage have not been determined. Anecdotal reports from people who have tried modafinil within the community suggest that there do not seem to be any negative health effects.
Not available.
Adrafinil is a stimulant based eugeroic that can increase energy, prevent fatigue, and enhance wakefulness, without causing anxiety or other side effects that are typically associated with stimulants. It may also improve mood, focus, and learning ability, and may even help keep your brain healthy.
Buy Now
Buy NowBuy NowBuy NowBuy NowBUY NOWBuy Now
I am yet to personally experiment with adrafinil, however, in the past I have used modafinil and noticed incredible effects for wakefulness and alertness.
