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Benefits

How To Use

Evidence

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Mitoburn (L-Baiba) - Exercise Mimicking Supplement

"Fire Up Your Metabolism Naturally"

L-BAIBA is great for athletes trying to get more out of their workout, casually active individuals looking to amplify diet and workout as well as those looking for healthy ways to get leaner and more fit. Naturally, scientists asked, “What happens if we supplement more BAIBA in these animals without exercise? Will it mimic some of the effects of exercise?” The answer was yes. Demonstrated and published in 2014, oral BAIBA supplementation activated many of the same “thermogenic programs” as exercise itself does.

Benefits

How To Use

Evidence

benefits

How

Mitoburn (L-Baiba) - Exercise Mimicking Supplement

can help you:

Increased conversion from energy-storing white adipose tissue to energy-burning brown-like adipose tissue. Increased fatty acid oxidation (fat burning.). Increased BHB levels (the primary ketone body generated when oxidizing fat). Protection against fat gain in mice that have low leptin levels. Improved insulin sensitivity and glucose tolerance. Prevention of disuse-based bone and muscle loss.

Fat Loss

  • Protection against fat gain in mice that have low leptin levels (1).
  • Improves insulin sensitivity and glucose tolerance (2).
  • Increases fatty acid oxidation (fat burning) and plasma beta-hydroxybutyrate (the primary ketone body generated when oxidizing fat (3).
  • There’s a possibility that BAIBA may reduce fat accumulation by decreasing LDL and triglyceride levels, and through increasing HDL levels in the body (4).
  • Increases brown fat levels, the beiging of white fat (5).

Longevity

  • Improve glucose tolerance and insulin sensitivity through AMP-activated protein kinase (AMPK) and PPARa (6).
  • Prevent disuse-based bone and muscle loss through the Mas-Related G Protein-Coupled Receptor Type D (MRGPRD) to prevent the breakdown of mitochondria and cell death due to reactive oxygen species (ROS)(7).
  • BAIBA levels increase in circulation in response to exercise, thus it serves as a contraction-induced myokine that increases energy expenditure and participates in exercise-induced protection from metabolic diseases (8).
DOSAGE STRATEGY

How to use

Mitoburn (L-Baiba) - Exercise Mimicking Supplement

250mg-500mg per day. 1-2 capsules.

General population:

250mg-500mg per day. 1-2 capsules.

Adults:

250mg-500mg per day. 1-2 capsules.

250mg-500mg per day. 1-2 capsules.
mg of

Ideal for:

Best used in the morning before fasted cardio or weight training. Alternatively, it can also be used on rest days.

Athletes, Fat Loss, Sports Performance

CAUTIONS

Mitoburn (L-Baiba) - Exercise Mimicking Supplement

safety and
medication interactions.

Safety assessment

In 2019, safety data was conducted on mice and showed L-BAIBA’s LD50 (lethal dose for 50% of animals) was well over 2,000mg/kg of body weight, which means we’re very comfortable with the suggested dose.

Safety studies

Not available.

Medication interactions

  • None known. Please consult your healthcare professional before using this supplement.

Side Effects / Contraindications

  • None known. Please consult your healthcare professional before using this supplement.

Allergies

  • None known. Please consult your healthcare professional before using this supplement.

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Increased conversion from energy-storing white adipose tissue to energy-burning brown-like adipose tissue. Increased fatty acid oxidation (fat burning.). Increased BHB levels (the primary ketone body generated when oxidizing fat). Protection against fat gain in mice that have low leptin levels. Improved insulin sensitivity and glucose tolerance. Prevention of disuse-based bone and muscle loss.

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L-Baiba, I find, can be used to accelerate fat loss similar to other compounds like Bitter Melon, Cinnamon and Metformin. It enhances brown fat production, which I like.

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Scientific Citations

1
β-Aminoisobutyric Acid Induces Browning of White Fat and Hepatic β-Oxidation and Is Inversely Correlated with Cardiometabolic Risk Factors
2
BAIBA attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK–PPARδ-dependent pathway in mice
3
Effects of Zidovudine, Stavudine and Beta-Aminoisobutyric Acid on Lipid Homeostasis in Mice: Possible Role in Human Fat Wasting
4
Effects of Zidovudine, Stavudine and Beta-Aminoisobutyric Acid on Lipid Homeostasis in Mice: Possible Role in Human Fat Wasting
5
β-aminoisobutyric Acid, L-BAIBA, Is a Muscle-Derived Osteocyte Survival Factor
6
β-Aminoisobutyric Acid Induces Browning of White Fat and Hepatic β-Oxidation and Is Inversely Correlated with Cardiometabolic Risk Factors
7
β-aminoisobutyric Acid, L-BAIBA, Is a Muscle-Derived Osteocyte Survival Factor
8
Quantification of aminobutyric acids and their clinical applications as biomarkers for osteoporosis