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Developed in the Soviet Union for the needs of the military, Bemitil (also known as Metaprot and AntiHot) has a long history of usage in clinical practice and in sport. It was developed in the 1970s and was successfully used during Afghanistan war, Chernobyl catastrophe and Olympic games in Moscow.
The chemical structure of Bemitil is similar to that of nucleobases adenine and guanine, which can explain its pharmacological effects. Bemitil does increase the expression of RNA and proteins in the skeletal muscle, brain cells, liver, and kidneys. It also stimulates ATP formation and gluconeogenesis. Gluconeogenesis is the process of formation of glucose from non-carbohydrate substrates, such as lactate, fats and glucogenic amino acids, which plays an important role in the energy supply during exercise. Fasting, physical exercises and a low-carb diet rich in proteins and fats have also shown to stimulate gluconeogenesis.
• Possesses adaptogenic effects, allowing the organism to respond more efficiently to stressors, be it mental or physical (1).
• It reduces the lactate (the limiting performance factor) as well as the resynthesis of carbohydrates (a source of energy leading to an increase in physical performance)(2).
• Actoprotectors can be widely used for recovery of work capacity, not only by healthy people but also by asthenic patients afflicted with various diseases (2).
• Bemitil penetrates the blood-brain barrier (2).
• Bemitil or Metaprot is an adaptogenic drug with nootropic, regenerative, antihypoxic, antioxidant and immunomodulatory effects (2).
• Experimental research has established that single and course administration of bemitil effectively increases the physical work capacity of animals and accelerates rehabilitation after exertion under exhaustive loads (3).
• Significantly increases maximal volume of the performed work (+33%) and resistance of mice for tiredness (+60%). Thus, the maximum stimulative effect of bemitil is observed in the considerable tiredness phase (3).
• It activates the synthesis of RNA and then proteins, including enzymes and ones related to the immune system (2).
General population:
100mg-250mg, orally, after a meal.
Adults:
100mg-250mg, orally, after a meal.
Ideal for:
The drug should be taken by a 5-days course. To avoid accumulation, another 5-day days course is suggested after a two days break.
Athletes, Sports performance.
The frequency of side effects: very often (above 10%), often (1-10%), infrequent (0.1-1%), rare (0.01-0.1%), very rare (<0.01%, including isolated cases with undefined frequency).
Not available.
The chemical structure of Bemitil is similar to that of nucleobases adenine and guanine, which can explain its pharmacological effects. Bemitil does increase the expression of RNA and proteins in the skeletal muscle, brain cells, liver, and kidneys. It also stimulates ATP formation and gluconeogenesis. Gluconeogenesis is the process of formation of glucose from non-carbohydrate substrates, such as lactate, fats and glucogenic amino acids, which plays an important role in the energy supply during exercise. Fasting, physical exercises and a low-carb diet rich in proteins and fats have also shown to stimulate gluconeogenesis.
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This is something that I am BUSTING to try. My friend was able to trial it before me and he reported benefits in cycling endurance. It's great to see Bemethyl available in Australia.
